The Department of Biochemistry and Biomedical Sciences (BBS), which exists within the faculties of Science and Health Sciences at McMaster University, is known for its world-class researchers and professors. You might have a course taught by them or wish to carry out research in their labs. Begin by searching for a professor or area of interest, or by scrolling through the list below. Select an image to learn more. For more information, see the Biochemistry and Biomedical Sciences Faculty Directory.
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Dr. Andres is interested in understanding the molecular mechanisms of bacterial DNA damage response and repair and the role these interactions play in driving the evolution of antimicrobial resistance.
Dr. Bhatia is interested in human somatic and pluripotent stem cell development on a molecular level. More specifically, he focuses on characterization of pathways that govern such cells, including self-renewal and differentiation mechanisms, while employing novel in vivo models for cell and tissue regeneration.
The Bishop lab focuses on bacterial cell envelope biogenesis and mechanics, including lipid transport and signal transduction.
The Bowdish lab studies the process of macrophage phagocytosis, how macrophages influence the composition of the microbiome of the upper respiratory tract and how they recognize and destroy Streptococcus pneumoniae, the major cause of pneumonia in the elderly.
Source: The Bowdish Lab
Dr. Brown works on bacterial molecular genetics, with a special interest in a biochemical approach to understanding and combatting antibiotic resistance, in addition to bacterial cell structure biogenesis.
Source: Brown Lab
The Burrows lab studies the Type IV Pili and Type II Secretion systems of Pseudomonas aeruginosa in a drug development context, in addition to examining biofilm development.
Source: Burrows Lab
Dr. Coombes works on understanding the relationship between pathogenic bacteria and their hosts, and how this relationship changes biologically and physiologically with respect to pathology and immunology. His lab in particular has a special interest in GI tract diseases.
Source: Coombes Lab
The Doble lab studies stem cells, including cell signaling, differentiation, live-cell imaging, and targeted gene manipulation.
The Gupta lab identifies novel molecular markers through examination of the cellular genome.
Dr. Hassell studies the PEA3 subfamily of mammalian Ets proteins, which are active in mammary gland development and oncogenesis.
The Hope lab examines the mechanisms of Hematopoietic Stem Cell (HSC) renewal in both normal and leukemic contexts.
Dr. Li studies the various applications of single-stranded DNA and RNA (ssDNA, ssRNA) including catalytic and binding functions. Additionally, the Li Lab creates novel ssDNA/ssRNA molecules with the intention of screening for novel functions.
As a new member to SCC-RI, Dr. Lu utilizes proteomics and systems biology to study alternative splicing regulatory mechanisms to profile splicing isoforms, characterize splicing factors, and pinpoint signaling pathways of differentiation of pluripotent human embryonic stem cells and iPSC.
The MacNeil lab studies the impacts of diet and microbiota on larger-scale factors, including health and development and disease susceptibility and progress. The MacNeil lab uses high-throughput screening to identify key genes that modify an organism's response to specific environmental factors, and often uses the nematode C. elegans as a model organism.
A joint professor within the Department of Chemistry and Chemical Biology, Dr. Magarvey studies metabolomics and small molecule signaling in biochemical pathways.